Research / Articles
Alzheimer's Disease and Periodontal Disease: Mechanisms Underlying A Potential Bi-Directional Relationship
Grand Rounds in Oral-Systemic Medicine - September 2006
Pamela S. Stein, DMD; Stephen Scheff, PhD; Dolph R. Dawson III, DMD, MS
"Numerous studies support a link between oral and systemic disease. Recent data also suggest that periodontal disease is a significant risk factor for Alzheimer’s disease. "
Alzheimer's disease - a neurospirochetosis. Analysis of the evidence following Koch's and Hill's criteria
Journal of Neuroinflammation - 2011
Judith Miklossy MD, PhD, DSc
"Researchers from Cortexyme and several universities have reported finding the two toxic enzymes that P. gingivalis uses to feed on human tissue in 99 and 96 per cent of 54 human Alzheimer’s brain samples taken from the hippocampus – a brain area important for memory."
We may finally know what causes Alzheimer’s – and how to stop it
New Scientist - January 2019
Deborah Mackenzie
"Researchers from Cortexyme and several universities have reported finding the two toxic enzymes that P. gingivalis uses to feed on human tissue in 99 and 96 per cent of 54 human Alzheimer’s brain samples taken from the hippocampus – a brain area important for memory."
Molecular and immunological evidence of oral Treponema in the human brain and their association with Alzheimer's disease
Journal of Molecular Oral Biology - March 2002
G. R. Riviere; K. H. Riviere; K. S. Smith
"These findings suggest that oral Treponema may infect the brain via branches of the trigeminal nerve."